Guests at the Sleep Inn Charleston are greeted in a bright and modern lobby, which features tall sloped ceilings and a large wooden front desk illuminated by a white rectangular light suspended over it. A beige couch and armchairs flank the front door and the room's neutral hues are enlivened by a cheery green accent wall decorated with a white tree branch pattern. Potted plants give the space a homey feel and a dispenser of lemon-infused water is a nice, attentive touch. The adjoining breakfast room is a fairly standard space typical of chain hotels, though clean and bright, with glass doors that open out onto a pretty outdoor patio with wrought iron tables and chairs under a vine-covered pergola.

The hotel shares a parking lot with the neighboring Best Western hotel and is located along the heavily congested Savannah Highway. There are several local business nearby including a car wash, gas stations, and car dealerships, as well as a couple of dining options that are within walking distance like an iHop, diner, and barbecue place. Attractions in downtown Charleston like Aquarium Wharf and City Market are within a 20-minute drive, and the airport is also about 20 minutes away.

Rooms at the hotel are bright and spacious, with contemporary decor that includes black-and-white framed photos adorning mint-green accent walls, sleek wooden headboards, and brown bedding with floral runners. Rooms have dark wood work desks and wardrobes, as well as modern amenities like flat-screen TVs, coffeemakers, microwaves, mini-fridges, and free Wi-Fi. Sinks are located in a separate area outside of the small bathrooms which have walk-in showers, while ADA-compliant rooms have shower/tub combinations.

The hotel's sparse amenities are limited to a free continental breakfast that includes yogurt, hard-boiled eggs, and waffles, which is served in a bright dining room that opens out onto a lovely little outdoor patio with tables and chairs. The hotel also offers free parking and Wi-Fi, and there’s a small business center with one computer and printer/fax machine. Pets are allowed for an additional fee.