The motel is located within walking distance of many popular attractions in Key West, including busy Duval Street. The lobby includes a wood-paneled front desk, and a bright-pink hibiscus flower painting hangs above a small sitting area, near a sofa and wicker coffee table. There are also a small desk with two public-use computers, and a breakfast buffet bar with seating.

The rooms form a square, enclosing the hot tub and large L-shaped heated outdoor pool in the center of the property. This mid-range property lacks upscale furnishings and some on-site amenities (there isn't a gym), but rates are reasonable given the motel's central location. There are no on-site restaurants serving lunch or dinner, but the motel offers room service and there are several restaurants within walking distance.

The Best Western Hibiscus is located on Simonton Street in an area with several other hotels and restaurants. There is a convenience store around the corner, and several restaurants are located within three blocks, including Abbondanza Italian Restaurant, Banana Café, and Camille's Restaurant (a popular spot for breakfast or lunch). The property is one block from the quieter end of Duval Street and situated within 10 to 15 blocks of Duval's more popular dining, shopping, and nightlife areas. Southernmost Point, Southernmost Beach, Key West Butterfly and Nature Conservatory, and various water sport companies are located within three to five blocks of the motel. The Ernest Hemingway Home and Museum and the Key West Lighthouse and Keeper's Quarters Museum are about eight blocks away. For those looking to venture farther, the motel is one block from a stop along the Old Town Trolley Tour, a convenient way of traveling among Key West's tourist attractions.

Poolside rooms have a view of the pool and patio area, while exterior-facing rooms look out over the busy street below. Standard Rooms are medium-size, while suites are slightly larger with an additional living and dining area. Rooms have tropical decor with brightly colored walls, palm tree-printed throw pillows with matching bedspreads, and a painting of the property's signature pink hibiscus flower. All rooms have mini-fridges and microwaves, small sitting and desk areas, flat-screen TVs, and free Wi-Fi. Outside the bathroom, there is a large vanity mirror and sink with plenty of counterspace, plus a coffeemaker. Bathrooms are small but were renovated with a shower/bathtub combination and a second sink with a medium-sized vanity mirror.

The motel is centered around a large, L-shaped heated outdoor pool and hot tub. There are plenty of lounge chairs and tables with bright red umbrellas. Breakfast is served buffet-style in the lobby each morning, with options such as cereal, fruit, yogurt, and eggs. There are few tables available indoors, so guests may choose to take their breakfast to-go or dine at one of the outdoor tables on the pool's patio. There's an on-site business center, free parking, and free Wi-Fi.