The exterior of the Strand Palace embraces the Edwardian architecture of the early 20th century, which simplified the details of Victorian design yet maintained elements such as bold decorative molding and sloping gray shingled roofs. The hotel was redesigned in the 1920s with Art Deco decor, some of which still remains, including a flowery brass staircase that leads guests to rooms and a dramatically lit stairway. The lobby has a contemporary style. Its three restaurants, two bars, and cafe all have a slightly different style, but most riff on traditional upscale hotel decor. This property attracts a mix of business travelers and tourists.

The hotel is located on The Strand, one of the busiest streets in the city center, within a short walk of numerous popular attractions. Several West End theaters, such as the Lyceum and Royal Opera House, are within a 10-minute walk from the property. The famous Covent Garden open-air market is a five-minute walk from the hotel. The Convent Garden underground station is a six-minute walk from the hotel and Charing Cross is eight minutes away on foot. Larger attractions, such as Buckingham Palace, are about 15 to 20 minutes by tube or bus. The Tower of London is a 20-minute tube ride away. Getting to Gatwick Airport takes around an hour without traffic, while Heathrow is about 45 minutes away, traffic permitting.

By far the most impressive amenities of the hotel are its three restaurants, two bars, and a cafe. A buffet breakfast with pancakes is offered for a fee and receives mixed reviews. Room service is available 24 hours. Dining aside, there's a decent gym with treadmills, weight machines, and free weights. The business center has computers, printers, and a photocopier. Free Wi-Fi is available throughout the hotel.