The upscale Hesperia Madrid offers spacious and comfortable rooms with fun design accents and great amenities, including flat-screen TVs, quality mattresses, minibars, and big marble bathrooms. The hotel features solid conveniences for families, such as baby kits, babysitting services, adjoining rooms, cots, and baby monitors. Adults will probably love the dining choices here, which include a Michelin-rated restaurant, Santceloni, a sushi bar, a cocktail bar, or room service. Location close to the Metro and lots of bus lines is convenient for visiting the attractions.

This mid-range hotel features updated rooms with flat-screen TVs, stocked minibars, free Wi-Fi, and hydro-massage showers. Family rooms with bunk beds and fair-trade gifts for kids make this hotel a good pick for families who want to be close to attractions. With a decent breakfast, free loaner bicycles, and in-room PCs available upon request, this is a solid option in a central location.

The 67-room Petit Palace Posada Del Peine is located in a historic building in the heart of Madrid, dating back to 1610. While the building has a real sense of history, the decor is quite modern. Perks for families include spacious rooms with bunk beds, hydro-massage showers, flat-screen TVs, and a large breakfast buffet. With free bike rentals, free Wi-Fi, and a location near Plaza Mayor, this hotel is a good pick for value and convenience.

The highlight of Petit Palace Alcala Torre is its fabulous location, within easy walking distance of restaurants, shops, and sights. The 59 bright rooms are up to date and attractive with flat-screen TVs, modern bathrooms, and free Wi-Fi. A variety of room categories includes triple rooms, with one large bed and bunk beds, and a duplex with a loft-style bedroom -- so families have plenty of options. Cribs are available upon request, and babysitting services can be arranged through the concierge. The rooms' minimalist, contemporary decor continues in the lobby and the sunny breakfast room as well. Though this 15-story building has elevators, there are quite a few stairs to climb before reaching them. This is a solid pick in Madrid's historic area for location and value.

The Hotel Villa Real is among the most luxurious hotels in Madrid, but despite its upscale and artsy vibe, this is a hotel that caters to families. The hotel offers spacious rooms that can be connected for extra space and added convenience, as well as a kids’ menu, a varied breakfast buffet, and even an interesting art gallery of ancient art great for getting the kids in the mood for a day full of tourist activities. Babysitting services can be arranged through front desk.