Given its proximity, the hotel is frequented more by visiting academics and medical professionals than tourists, but it's close enough to rail and metro stations to make it a suitable option for visitors willing to trade a central location for lower rates. The hotel has an open reception area adorned with brightly colored hanging lights, long torch-like sconces, and patterned couches. A desktop computer sits on a wooden desk. There's plenty of tourist information and guide books on hand for guests to peruse.

A bit off the tourist track in southeast of Rome, the Hotel delle Province is close to the University of Rome La Sapienza, a hospital, and the Termini and Tiburtina railway stations. It's a busy, noisy neighborhood, filled restaurants and cafes frequented by students and local residents. The Tiburtina railway station is within a five-minute walk from the hotel, and the Termini metro and railway stations are within a 20-minute walk, putting Rome's historic center within easy reach. Sights such as the Villa Borghese and Piazza del Popolo are four metro stops away via the MEA line from Termini to Spagna station. From here, travelers can walk along the main shopping areas of Via del Corso and Via Condotti. The Spanish Steps are a short ways from Via Condotti, and reachable from the Spagna station. Vatican City, with its museums and gardens, is a 20-minute drive from the hotel, and is reachable via the metro at Ottaviano station. Ciampino Airport is a  24-minute drive from the hotel. 

There are 46 rooms: Junior Suite, Suite, Single, Double, and Triple Rooms. Each comes with a hairdryer, air-conditioning, minibar, coffeemaker, flat-screen smart TV with Internet and satellite channels, and free Wi-Fi connectivity. Junior Suites and Suites have king size beds, sofa beds, and cardio machines, along with balconies with patio seating. Standard Rooms have either a bathtub or shower in the bathrooms. Those with walk-in showers have rain-shower shower heads, but they are on the small side. Some rooms overlook the street. 

Breakfast, included in the room rate, is served every morning in the rooftop garden dining area, and includes fruits, pastries, cheese, sausages, tea, and coffee. There isn't a bar or restaurant on-site. Wi-Fi is free and available throughout the property. There's a computer for guests' use in the lobby, for a fee. There is no fitness center on site, but the Junior Suites and Suites have compact step machines tucked away in the closet, and cardio bikes in a corner of the room.