For those who can afford it, the four-pearl Inn on Biltmore Estate delivers a memorable experience. The stately property that opened in 2001 on the grounds of the world-famous Biltmore Estate offers spectacular views around every corner from its hilltop perch. Highlights of its extensive amenities package include fine dining, a full-service spa, pool, and fitness center. Its 210 guest rooms are traditionally decorated, spacious, and nicely appointed, with Keurig coffeemakers, robes, nightly turndown, and marble bathrooms. Some units include balconies and separate walk-in showers and whirlpool tubs. But the grand experience comes at a hefty price that doesn’t include admission to the Biltmore Estate.

Ideal for guests who appreciate luxury surroundings with creative flair, Asheville’s edition of the Grand Bohemian Autograph Collection delivers. The 104-room Tudor-style property is conveniently located directly across from the Biltmore Estate. Cozy rustic charm is seen throughout, with taxidermy, stacked stone, and candlelight. There's a restaurant and lounge hosting live music twice a week, a spa offering locally inspired treatments, and an on-site art gallery with work by local and international artists. Guest rooms are modern and plush, with stunning bathrooms, unique artwork, and velvet-tufted headboards -- but compared to many surrounding hotels, the price tag is high and there is no pool.

The Grove Park Inn is geared toward luxury travelers and has the price tag to prove it, along with expensive meals and valet parking. The upscale 513-room hotel is spectacularly beautiful inside and out; built from stacked stones and dating back more than 100 years, it is surrounded by one of the most revered golf courses in the area, and comes equipped with an enormous spa and several restaurants and bars. In addition, there are spacious indoor and outdoor pools, tennis courts, and a National Geographic-approved outdoor adventure center on-site. Guest rooms are elegant and cozy, with period Arts and Crafts furnishings and views of the mountains or courtyard through lovely, wood-trimmed windows. Kids' programs and camps are offered daily and nightly.