Great John Street Hotel is located in a lovely old Victorian schoolhouse that's been renovated with real panache -- interiors effortlessly blend original fixtures with vintage and contemporary pieces. Many of the 30 chic and eclectic rooms have duplex levels with single or twin roll-top bathtubs, while others have polished iron fireplaces and separate lounge areas. King-sized beds have handmade double pocket sprung mattresses and in-room tech includes flat-screen TVs, iPod docks, and free Wi-Fi. Hotel features include the Roof Garden Playground, where guests can unwind with a drink or take a dip in the outdoor wooden hot tub, the vintage-inspired Oyster Bar on the ground floor, and the homey Library & Terrace, which has a fire-burning stove. 

Located in the heart of Manchester's gay district, the 19-room Velvet is within walking distance of Chinatown and the Piccadilly railway station. Rooms are uniquely decorated with rich fabrics, pop art, and a blend of modern and antique-style furnishings. In-room amenities include flat-screen TVs with DVD players, luxury REN toiletries, and free Wi-Fi. Penthouse suites have separate seating areas, freestanding roll-top bathtubs, and loft-level beds. The Velvet serves a la carte breakfasts, classic British cuisine, and Sunday roasts in its stylish basement restaurant, while tits exuberant Velvet Lounge Bar has live DJs on weekends. Noise can be an issue when the nightlife really gets going, so those looking for a less energetic hotel might prefer Great John Street, which is located in a quiet area of Manchester center next to Coronation Street Studios.

The stylish Abode Manchester is housed in a beautiful Victorian red-brick building that was once a textile factory. The hotel has been given a modern overhaul, with crisp white-and-gray decor plus large contemporary paintings that add a hip edge. Touches of the past remain in the industrial exposed pipework and vertical radiators, as well as the intricate chandeliers and ornate gilt-framed mirrors. The 61 rooms have funky loft-like style with faux-bookshelf wallpaper and plaid wood throws and original features, like parquet flooring). All rooms feature flat-screen TVs, kettles, and free Wi-Fi. Certain room types come with things like minibars, sofas, and gaming consoles, and suites add Nespresso machines and Bose sound systems. While this hotel goes big on style, common features are limited. Adobe has a stylish, bi-level brasserie with an all-day European menu and room service. There are live DJs and music on the weekends, and cocktail masterclasses are available for groups. 

Etrop Grange is a listed heritage building dating back to 1780 with Georgian charm in tact. The hotel has the atmosphere of a country home and traditional style, with wood paneling, chandeliers, and marble fireplaces in public spaces and antique furniture in the 64 rooms. The Grange Bar & Grill has a dining room overlooking a courtyard and The Library for private dining. Traditional English breakfast is available for an extra fee. While the other hotels are in the city center, Etrop is minutes from Manchester Airport (hotel provides free shuttle service) and is a half-hour from city center; buses to Manchester stop just outside the hotel.